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JAK2 rabbit pAb

This gene product is a protein tyrosine kinase involved in a specific subset of Cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. [provided by RefSeq, Jul 2008],

Product Specifications

Background

This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. [provided by RefSeq, Jul 2008]

Synonyms

JAK2; Tyrosine-protein kinase JAK2; Janus kinase 2; JAK-2

Gene ID

3717

UniProt

O60674

Cellular Locus

Endomembrane system ; Peripheral membrane protein. Cytoplasm. Nucleus.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human JAK2. AA range:981-1030

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

IF, WB, IHC, ELISA

Validated Applications

IF,WB,IHC,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

IF: 1:50-200 Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Molecular Weight

130kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES2656-1.pdf

Observed Molecular Weight

130 kD

Subcellular Location

Endomembrane system ; Peripheral membrane protein . Cytoplasm . Nucleus .

Other Product Names

JAK2; Tyrosine-protein kinase JAK2; Janus kinase 2; JAK-2

Gene ID (Human)

3717

SwissProt (Human)

O60674

Available Sizes

Curated Selection

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