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IQGAP1 rabbit pAb

IQ motif containing GTPase activating protein 1 (IQGAP1) Homo sapiens This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines. [provided by RefSeq, Jul 2008],

Product Specifications

Background

IQ motif containing GTPase activating protein 1 (IQGAP1) Homo sapiens This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines. [provided by RefSeq, Jul 2008]

Product Name Alternative

IQGAP1; KIAA0051; Ras GTPase-activating-like protein IQGAP1; p195

UniProt

P46940

Swiss Prot

P46940

Reactivity

Human; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human IQGAP1. AA range:247-296

Target

IQGAP1

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC

Concentration

1 mg/ml

Dilution

WB 1:500-2000; IHC-p 1:50-300

Buffer

-20°C/1 year

Molecular Weight

190kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

190kD

Fragment

IgG

Subcellular Location

Cell membrane . Nucleus . Cytoplasm . Subcellular distribution is regulated by the cell cycle, nuclear levels increase at G1/S phase (PubMed:20883816) . .

Other Product Names

IQGAP1; KIAA0051; Ras GTPase-activating-like protein IQGAP1; p195

Gene ID (Human)

8826

Available Sizes

Curated Selection

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