IL-11Rα rabbit pAb

Interleukin 11 is a stromal cell-derived Cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor, which is a member of the hematopoietic Cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a Cytokine receptor-like domain. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012],

Product Specifications

Background

Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012]

Product Name Alternative

IL11RA; Interleukin-11 receptor subunit alpha; IL-11 receptor subunit alpha; IL-11R subunit alpha; IL-11R-alpha; IL-11RA

UniProt

Q14626

Swiss Prot

Q14626

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from IL-11Rα . at AA range: 300-380

Target

IL-11Rα

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Buffer

-20°C/1 year

Molecular Weight

45kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

45kD

Fragment

IgG

Subcellular Location

[Interleukin-11 receptor subunit alpha]: Membrane ; Single-pass type I membrane protein .; [Soluble interleukin-11 receptor subunit alpha]: Secreted .; [Isoform HCR2]: Secreted .