Ikaros 3 rabbit pAb
This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. [provided by RefSeq, Apr 2012],
Product Specifications
Background
Product Name Alternative
IKZF3; ZNFN1A3; Zinc finger protein Aiolos; Ikaros family zinc finger protein 3
UniProt
Q9UKT9
Swiss Prot
Q9UKT9
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human IKZF3. AA range:361-410
Target
Ikaros 3
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
62kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
62kD
Fragment
IgG
Subcellular Location
Other Product Names
IKZF3; ZNFN1A3; Zinc finger protein Aiolos; Ikaros family zinc finger protein 3
Gene ID (Human)
22806
Available Sizes
Frequently Asked Questions
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