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IGSF4D rabbit pAb

Cell adhesion molecule 2 (CADM2) Homo sapiens This gene encodes a member of the synaptic Cell adhesion molecule 1 (SynCAM) family which belongs to the immunoglobulin (Ig) superfamily. The encoded protein has three Ig-like domains and a cytosolic protein 4. 1 binding site near the C-terminus. Proteins belonging to the protein 4. 1 family crosslink spectrin and interact with other cytoskeletal proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012],

Product Specifications

Background

Cell adhesion molecule 2 (CADM2) Homo sapiens This gene encodes a member of the synaptic cell adhesion molecule 1 (SynCAM) family which belongs to the immunoglobulin (Ig) superfamily. The encoded protein has three Ig-like domains and a cytosolic protein 4.1 binding site near the C-terminus. Proteins belonging to the protein 4.1 family crosslink spectrin and interact with other cytoskeletal proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]

Synonyms

CADM2; IGSF4D; NECL3; Cell adhesion molecule 2; Immunoglobulin superfamily member 4D; IgSF4D; Nectin-like protein 3; NECL-3; Synaptic cell adhesion molecule 2; SynCAM 2

Gene ID

253559

UniProt

Q8N3J6

Cellular Locus

Cell membrane ; Single-pass type I membrane protein. Cell junction, synapse. Cell projection, axon. Found in the axoplasm of myelinated axons.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human CADM2. AA range:131-180

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, IHC, IF, ELISA

Validated Applications

WB,IHC,IF,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Molecular Weight

47kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES2597-1.pdf

Observed Molecular Weight

47 kD

Subcellular Location

Cell membrane ; Single-pass type I membrane protein . Cell junction, synapse . Cell projection, axon . Found in the axoplasm of myelinated axons.

Other Product Names

CADM2; IGSF4D; NECL3; Cell adhesion molecule 2; Immunoglobulin superfamily member 4D; IgSF4D; Nectin-like protein 3; NECL-3; Synaptic cell adhesion molecule 2; SynCAM 2

Gene ID (Human)

253559

SwissProt (Human)

Q8N3J6

Available Sizes

Curated Selection

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