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HSP β2 rabbit pAb

The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The protein is expressed preferentially in the heart and skeletal muscle. This protein regulates Myotonic Dystrophy Protein Kinase, which plays an important role in maintenance of muscle structure and function. [provided by RefSeq, Dec 2012],

Product Specifications

Background

The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The protein is expressed preferentially in the heart and skeletal muscle. This protein regulates Myotonic Dystrophy Protein Kinase, which plays an important role in maintenance of muscle structure and function. [provided by RefSeq, Dec 2012]

Synonyms

HSPB2; Heat shock protein beta-2; HspB2; DMPK-binding protein; MKBP

Gene ID

3316

UniProt

Q16082

Cellular Locus

Cytoplasm. Nucleus. Localizes to nuclear foci.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human HSPB2. AA range:121-170

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, IHC, IF, ELISA

Validated Applications

WB,IHC,IF,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.

Molecular Weight

24kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES2579-1.pdf

Observed Molecular Weight

24 kD

Subcellular Location

Cytoplasm . Nucleus . Localizes to nuclear foci.

Other Product Names

HSPB2; Heat shock protein beta-2; HspB2; DMPK-binding protein; MKBP

Gene ID (Human)

3316

SwissProt (Human)

Q16082

Available Sizes

Curated Selection

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