HPK1 rabbit pAb
Catalytic activity: ATP + a protein = ADP + a phosphoprotein. Cofactor: Magnesium. function: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. May play a role in hematopoietic lineage decisions and growth regulation. similarity: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. similarity: Contains 1 CNH domain. similarity: Contains 1 protein kinase domain. subunit: Interacts with MAP3K1. tissue specificity: Expressed primarily in hematopoietic organs, including bone marrow, spleen and thymus. Also expressed at very low levels in lung, kidney, mammary glands and small intestine.
Product Specifications
Background
Synonyms
Gene ID
11184
UniProt
Q92918
Cellular Locus
Intracellular,cytoplasm,membrane,
Host
Rabbit
Species Reactivity
Human,Mouse
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human MEKKK 1. AA range:371-420
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC, IF, ELISA
Validated Applications
WB,IHC,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
91kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES2564-1.pdf
Observed Molecular Weight
91 kD
Subcellular Location
Intracellular, cytoplasm, membrane
Other Product Names
Gene ID (Human)
11184
SwissProt (Human)
Q92918
Available Sizes
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