GPR120 rabbit pAb

This gene encodes a G protein-coupled receptor (GPR) which belongs to the rhodopsin family of GPRs. The encoded protein functions as a receptor for free fatty acids, including omega-3, and participates in suppressing anti-inflammatory responses and insulin sensitizing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012],

Product Specifications

Background

Product Name Alternative

O3FAR1; GPR120; GPR129; PGR4; Omega-3 fatty acid receptor 1; G-protein coupled receptor 120; G-protein coupled receptor 129; G-protein coupled receptor GT01; G-protein coupled receptor PGR4

UniProt

Q5NUL3

Swiss Prot

Q5NUL3

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human GPR120. AA range:221-270

Target

GPR120

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

Buffer

-20°C/1 year

Molecular Weight

38kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

38kD

Fragment

IgG

Subcellular Location

[Isoform 1]: Cell membrane ; Multi-pass membrane protein . Endosome membrane ; Multi-pass membrane protein . Lysosome membrane ; Multi-pass membrane protein . Sorted to late endosome/lysosome compartments upon internalization. .; [Isoform 2]: Cell membrane ; Multi-pass membrane protein . Endosome membrane ; Multi-pass membrane protein . Lysosome membrane ; Multi-pass membrane protein . Cell projection, cilium membrane ; Multi-pass membrane protein . Sorted to late endosome/lysosome compartments upon internalization (PubMed:22282525) . Specifically localizes to the primary cilium of undifferentiated adipocytes. Ciliary trafficking is TULP3-dependent. As the cilium is lost during adipogenesis, moves to the plasma membrane (Probable) . .

Other Product Names

O3FAR1; GPR120; GPR129; PGR4; Omega-3 fatty acid receptor 1; G-protein coupled receptor 120; G-protein coupled receptor 129; G-protein coupled receptor GT01; G-protein coupled receptor PGR4