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GBP3 rabbit pAb

This gene encodes a member of the guanylate-binding protein (GBP) family. GBPs specifically bind guanine nucleotides (GMP, GDP, and GTP) and contain two of the three consensus motifs found in typical GTP-binding proteins. The encoded protein interacts with a member of the germinal center kinase family. Multiple transcript variants encoding different isoforms have been been found for this gene. [provided by RefSeq, Jan 2016],

Product Specifications

Background

This gene encodes a member of the guanylate-binding protein (GBP) family. GBPs specifically bind guanine nucleotides (GMP, GDP, and GTP) and contain two of the three consensus motifs found in typical GTP-binding proteins. The encoded protein interacts with a member of the germinal center kinase family. Multiple transcript variants encoding different isoforms have been been found for this gene. [provided by RefSeq, Jan 2016]

Synonyms

GBP3; Guanylate-binding protein 3; GTP-binding protein 3; GBP-3; Guanine nucleotide-binding protein 3

Gene ID

2635

UniProt

Q9H0R5

Cellular Locus

Cytoplasm. Cytoplasm, perinuclear region. Golgi apparatus membrane. Heterodimers with GBP1, GBP2 and GBP5 localize in the compartment of the prenylated GBPs: with GBP1 in a vesicle-like compartment, with GBP2, around the nucleus and with GBP-5, at the Golgi apparatus..

Host

Rabbit

Species Reactivity

Human,Rat,Mouse,

Reactivity

Human; Rat; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human GBP3. AA range:481-530

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, IHC, IF, ELISA

Validated Applications

WB,IHC,IF,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Molecular Weight

64kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES2406-1.pdf

Observed Molecular Weight

64 kD

Subcellular Location

Cytoplasm . Cytoplasm, perinuclear region . Golgi apparatus membrane . Heterodimers with GBP1, GBP2 and GBP5 localize in the compartment of the prenylated GBPs: with GBP1 in a vesicle-like compartment, with GBP2, around the nucleus and with GBP-5, at the Golgi apparatus. .

Other Product Names

GBP3; Guanylate-binding protein 3; GTP-binding protein 3; GBP-3; Guanine nucleotide-binding protein 3

Gene ID (Human)

2635

SwissProt (Human)

Q9H0R5

Available Sizes

Curated Selection

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