GAP1-InsP4 BP rabbit pAb
This gene encodes a protein that binds inositol 1, 3, 4, 5-tetrakisphosphate and stimulates the GTPase activity of Ras p21. This protein functions as a negative regulator of the Ras signalling pathway. It is localized to the cell membrane via a pleckstrin homology (PH) domain in the C-terminal region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],
Product Specifications
Background
Synonyms
RASA3; Ras GTPase-activating protein 3; GAP1(IP4BP); Ins P4-binding protein
Gene ID
22821
UniProt
Q14644
Cellular Locus
Cell membrane.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human RASA3. AA range:247-296
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Molecular Weight
95kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES2397-1.pdf
Observed Molecular Weight
95 kD
Subcellular Location
Cell membrane.
Other Product Names
RASA3; Ras GTPase-activating protein 3; GAP1 (IP4BP) ; Ins P4-binding protein
Gene ID (Human)
22821
SwissProt (Human)
Q14644
Available Sizes
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