GAP1-InsP4 BP rabbit pAb

This gene encodes a protein that binds inositol 1, 3, 4, 5-tetrakisphosphate and stimulates the GTPase activity of Ras p21. This protein functions as a negative regulator of the Ras signalling pathway. It is localized to the cell membrane via a pleckstrin homology (PH) domain in the C-terminal region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],

Product Specifications

Background

This gene encodes a protein that binds inositol 1,3,4,5-tetrakisphosphate and stimulates the GTPase activity of Ras p21. This protein functions as a negative regulator of the Ras signalling pathway. It is localized to the cell membrane via a pleckstrin homology (PH) domain in the C-terminal region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

Product Name Alternative

RASA3; Ras GTPase-activating protein 3; GAP1 (IP4BP) ; Ins P4-binding protein

UniProt

Q14644

Swiss Prot

Q14644

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human RASA3. AA range:247-296

Target

GAP1-InsP4 BP

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

Buffer

-20°C/1 year

Molecular Weight

95kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

95kD

Fragment

IgG

Subcellular Location

Cell membrane.

Other Product Names

RASA3; Ras GTPase-activating protein 3; GAP1 (IP4BP) ; Ins P4-binding protein

Gene ID (Human)

22821

Available Sizes

Curated Selection

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