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Galectin-9 rabbit pAb

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein encoded by this gene is an S-type lectin. It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H&RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its associated immunodeficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008],

Product Specifications

Background

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein encoded by this gene is an S-type lectin. It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H&RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its associated immunodeficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]

UniProt

O00182

Swiss Prot

O00182

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human LEG9. AA range:51-100

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Molecular Weight

40kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

40kD

Fragment

IgG

Subcellular Location

Cytoplasm . Nucleus . Secreted . May also be secreted by a non-classical secretory pathway (By similarity) . Secreted by mesenchymal stromal cells upon IFNG stimulation (PubMed:23817958) . .; [Isoform 2]: Secreted .; [Isoform 3]: Secreted .

Other Product Names

LGALS9; Galectin-9; Gal-9; Ecalectin; Tumor antigen HOM-HD-21

Gene ID (Human)

3965

Available Sizes

Curated Selection

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