ETAR rabbit pAb
This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009],
Product Specifications
Background
Synonyms
EDNRA; ETA; ETRA; Endothelin-1 receptor; Endothelin A receptor; ET-A; ETA-R; hET-AR
Gene ID
1909
UniProt
P25101
Cellular Locus
Cell membrane; Multi-pass membrane protein.
Host
Rabbit
Species Reactivity
Human,Mouse,Monkey
Reactivity
Human; Mouse; Monkey
Immunogen
The antiserum was produced against synthesized peptide derived from human EDNRA. AA range:378-427
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC, IF, ELISA
Validated Applications
WB,IHC,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Molecular Weight
48kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES2305-1.pdf
Observed Molecular Weight
48 kD
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Other Product Names
EDNRA; ETA; ETRA; Endothelin-1 receptor; Endothelin A receptor; ET-A; ETA-R; hET-AR
Gene ID (Human)
1909
SwissProt (Human)
P25101
Available Sizes
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