ERCC4 rabbit pAb
The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6). [provided by RefSeq, Mar 2009],
Product Specifications
Background
Synonyms
Gene ID
2072
UniProt
Q92889
Cellular Locus
Nucleus. Chromosome. Localizes to sites of DNA damage..
Host
Rabbit
Species Reactivity
Human,Mouse
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human XPF. AA range:801-850
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
103kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES2292-1.pdf
Observed Molecular Weight
103 kD
Subcellular Location
Nucleus . Chromosome . Localizes to sites of DNA damage. .
Other Product Names
Gene ID (Human)
2072
SwissProt (Human)
Q92889
Available Sizes
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