ERCC4 rabbit pAb

The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6). [provided by RefSeq, Mar 2009],

Product Specifications

Background

Product Name Alternative

ERCC4; ERCC11; XPF; DNA repair endonuclease XPF; DNA excision repair protein ERCC-4; DNA repair protein complementing XP-F cells; Xeroderma pigmentosum group F-complementing protein

UniProt

Q92889

Swiss Prot

Q92889

Reactivity

Human; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human XPF. AA range:801-850

Target

ERCC4

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Buffer

-20°C/1 year

Molecular Weight

103kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

103kD

Fragment

IgG

Subcellular Location

Nucleus . Chromosome . Localizes to sites of DNA damage. .

Other Product Names

ERCC4; ERCC11; XPF; DNA repair endonuclease XPF; DNA excision repair protein ERCC-4; DNA repair protein complementing XP-F cells; Xeroderma pigmentosum group F-complementing protein