ERAB rabbit pAb
This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids and steroids, and is a subunit of mitochondrial ribonuclease P, which is involved in tRNA maturation. The protein has been implicated in the development of Alzheimer disease, and mutations in the gene are the cause of 17beta-hydroxysteroid dehydrogenase type 10 (HSD10) deficiency. Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Aug 2014],
Product Specifications
Background
Synonyms
Gene ID
3028
UniProt
Q99714
Cellular Locus
Mitochondrion. Mitochondrion matrix, mitochondrion nucleoid.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat,Monkey
Reactivity
Human; Mouse; Rat; Monkey
Immunogen
The antiserum was produced against synthesized peptide derived from human ERAB. AA range:111-160
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC, IF, ELISA
Validated Applications
WB,IHC,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Molecular Weight
27kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES2287-1.pdf
Observed Molecular Weight
27 kD
Subcellular Location
Mitochondrion . Mitochondrion matrix, mitochondrion nucleoid .
Other Product Names
Gene ID (Human)
3028
SwissProt (Human)
Q99714
Available Sizes
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