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ENX-2 rabbit pAb

Enhancer of zeste 1 polycomb repressive complex 2 subunit (EZH1) Homo sapiens EZH1 is a component of a noncanonical Polycomb repressive complex-2 (PRC2) that mediates methylation of histone H3 (see MIM 602812) lys27 (H3K27) and functions in the maintenance of embryonic stem cell pluripotency and plasticity (Shen et al. 2008 [PubMed 19026780]). [supplied by OMIM, Mar 2009],

Product Specifications

Background

Enhancer of zeste 1 polycomb repressive complex 2 subunit (EZH1) Homo sapiens EZH1 is a component of a noncanonical Polycomb repressive complex-2 (PRC2) that mediates methylation of histone H3 (see MIM 602812) lys27 (H3K27) and functions in the maintenance of embryonic stem cell pluripotency and plasticity (Shen et al., 2008 [PubMed 19026780]) .[supplied by OMIM, Mar 2009]

Synonyms

EZH1; KIAA0388; Histone-lysine N-methyltransferase EZH1; ENX-2; Enhancer of zeste homolog 1

Gene ID

2145

UniProt

Q92800

Cellular Locus

Nucleus. Colocalizes with trimethylated 'Lys-27' of histone H3.

Host

Rabbit

Species Reactivity

Human,Mouse,Monkey

Reactivity

Human; Mouse; Monkey

Immunogen

The antiserum was produced against synthesized peptide derived from human EZH1. AA range:171-220

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, IHC, IF, ELISA

Validated Applications

WB,IHC,IF,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.

Molecular Weight

85kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES2265-1.pdf

Observed Molecular Weight

85 kD

Subcellular Location

Nucleus . Colocalizes with trimethylated 'Lys-27' of histone H3.

Other Product Names

EZH1; KIAA0388; Histone-lysine N-methyltransferase EZH1; ENX-2; Enhancer of zeste homolog 1

Gene ID (Human)

2145

SwissProt (Human)

Q92800

Available Sizes

Curated Selection

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