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EMR4 rabbit pAb

This gene is a member of the EGF-TM7 receptor gene family which is thought to play a role in leukocyte adhesion and migration. In other vertebrates, including nonhuman primates, this gene encodes a protein containing N-terminal EGF domains and a C-terminal transmembrane domain. Sequence evidence for the human gene, however, indicates nucleotide deletion in the genomic sequence would result in frameshift and early termination of translation. A protein expressed by this gene would be soluble rather than expressed on the cell surface. As the encoded protein has not been detected, this gene may represent a transcribed pseudogene. [provided by RefSeq, Aug 2008],

Product Specifications

Background

This gene is a member of the EGF-TM7 receptor gene family which is thought to play a role in leukocyte adhesion and migration. In other vertebrates, including nonhuman primates, this gene encodes a protein containing N-terminal EGF domains and a C-terminal transmembrane domain. Sequence evidence for the human gene, however, indicates nucleotide deletion in the genomic sequence would result in frameshift and early termination of translation. A protein expressed by this gene would be soluble rather than expressed on the cell surface. As the encoded protein has not been detected, this gene may represent a transcribed pseudogene. [provided by RefSeq, Aug 2008]

Synonyms

EMR4P; EMR4; GPR127; PGR16; Putative EGF-like module-containing mucin-like hormone receptor-like 4; EGF-like module receptor 4; G-protein coupled receptor 127; G-protein coupled receptor PGR16

Gene ID

326342

UniProt

Q86SQ3

Cellular Locus

[Isoform 1]: Cell membrane ; Multi-pass membrane protein.; [Isoform 2]: Secreted.

Host

Rabbit

Species Reactivity

Human,Monkey

Reactivity

Human; Monkey

Immunogen

The antiserum was produced against synthesized peptide derived from human EMR4P. AA range:101-150

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, IF, ELISA

Validated Applications

WB,IF,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Molecular Weight

55kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES2259-1.pdf

Observed Molecular Weight

55 kD

Subcellular Location

[Isoform 1]: Cell membrane ; Multi-pass membrane protein .; [Isoform 2]: Secreted .

Other Product Names

EMR4P; EMR4; GPR127; PGR16; Putative EGF-like module-containing mucin-like hormone receptor-like 4; EGF-like module receptor 4; G-protein coupled receptor 127; G-protein coupled receptor PGR16

Gene ID (Human)

326342

SwissProt (Human)

Q86SQ3

Available Sizes

Curated Selection

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