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Dok-2 rabbit pAb

Docking protein 2 (DOK2) Homo sapiens The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210 (bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq, Jul 2008],

Product Specifications

Background

Docking protein 2 (DOK2) Homo sapiens The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210 (bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq, Jul 2008]

UniProt

O60496

Swiss Prot

O60496

Reactivity

Human; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human p56 Dok-2. AA range:266-315

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Molecular Weight

46kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

46kD

Fragment

IgG

Subcellular Location

Cytosol

Other Product Names

DOK2; Docking protein 2; Downstream of tyrosine kinase 2; p56 (dok-2)

Gene ID (Human)

9046

Available Sizes

Curated Selection

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