CYP8B1 rabbit pAb
This gene encodes a member of the Cytochrome P450 superfamily of enzymes. The Cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7-alpha, 12-alpha-dihydroxy-4-cholesten-3-one. The balance between these two steroids determines the relative amounts of cholic acid and chenodeoxycholic acid both of which are secreted in the bile and affect the solubility of cholesterol. This gene is unique among the Cytochrome P450 genes in that it is intronless. [provided by RefSeq, Jul 2008],
Product Specifications
Background
UniProt
Q9UNU6
Swiss Prot
Q9UNU6
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human Cytochrome P450 8B1. AA range:371-420
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Molecular Weight
58kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
58kD
Fragment
IgG
Subcellular Location
Endoplasmic reticulum membrane ; Single-pass membrane protein . Microsome membrane ; Single-pass membrane protein .
Other Product Names
Gene ID (Human)
1582
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
