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Cyclin M2 rabbit pAb

Cyclin and CBS domain divalent metal cation transport mediator 2 (CNNM2) Homo sapiens This gene encodes a member of the ancient conserved domain containing protein family. Members of this protein family contain a cyclin box motif and have structural similarity to the cyclins. The encoded protein may play an important role in magnesium homeostasis by mediating the epithelial transport and renal reabsorption of Mg2+. Mutations in this gene are associated with renal hypomagnesemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011],

Product Specifications

Background

Cyclin and CBS domain divalent metal cation transport mediator 2 (CNNM2) Homo sapiens This gene encodes a member of the ancient conserved domain containing protein family. Members of this protein family contain a cyclin box motif and have structural similarity to the cyclins. The encoded protein may play an important role in magnesium homeostasis by mediating the epithelial transport and renal reabsorption of Mg2+. Mutations in this gene are associated with renal hypomagnesemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

Synonyms

CNNM2; ACDP2; Metal transporter CNNM2; Ancient conserved domain-containing protein 2; Cyclin-M2

Gene ID

54805

UniProt

Q9H8M5

Cellular Locus

Cell membrane ; Multi-pass membrane protein.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human CNNM2. AA range:571-620

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, ELISA

Validated Applications

WB,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Molecular Weight

100kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES2088-1.pdf

Observed Molecular Weight

100 kD

Subcellular Location

Cell membrane ; Multi-pass membrane protein .

Other Product Names

CNNM2; ACDP2; Metal transporter CNNM2; Ancient conserved domain-containing protein 2; Cyclin-M2

Gene ID (Human)

54805

SwissProt (Human)

Q9H8M5

Available Sizes

Curated Selection

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