CUG-BP1 rabbit pAb
CUGBP, Elav-like family member 1 (CELF1) Homo sapiens Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. This gene may play a role in myotonic dystrophy type 1 (DM1) via interactions with the dystrophia myotonica-protein kinase (DMPK) gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Synonyms
Gene ID
10658
UniProt
Q92879
Cellular Locus
Nucleus. Cytoplasm. RNA-binding activity is detected in both nuclear and cytoplasmic compartments.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human CELF-1. AA range:71-120
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC, IF, ELISA
Validated Applications
WB,IHC,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Molecular Weight
52kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES2071-1.pdf
Observed Molecular Weight
52 kD
Subcellular Location
Nucleus . Cytoplasm . RNA-binding activity is detected in both nuclear and cytoplasmic compartments.
Other Product Names
Gene ID (Human)
10658
SwissProt (Human)
Q92879
Available Sizes
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