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Connexin 25 rabbit pAb

Connexins, such as GJB7, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits (Sohl et al. 2003 [PubMed 12881038]). [supplied by OMIM, Mar 2008],

Product Specifications

Background

Connexins, such as GJB7, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits (Sohl et al., 2003 [PubMed 12881038]) .[supplied by OMIM, Mar 2008]

Product Name Alternative

GJB7; CX25; Gap junction beta-7 protein; Connexin-25; Cx25

UniProt

Q6PEY0

Swiss Prot

Q6PEY0

Reactivity

Human; Rat; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human GJB7. AA range:21-70

Target

Connexin 25

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Buffer

-20°C/1 year

Molecular Weight

24kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

24kD

Fragment

IgG

Subcellular Location

Cell membrane ; Multi-pass membrane protein . Cell junction, gap junction .

Other Product Names

GJB7; CX25; Gap junction beta-7 protein; Connexin-25; Cx25

Gene ID (Human)

375519

Available Sizes

Curated Selection

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