COL2A1 rabbit pAb
This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene. [provided by RefSeq, Jul 2008],
Product Specifications
Background
UniProt
P02458
Swiss Prot
P02458
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human Collagen II. AA range:101-150
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Molecular Weight
140kD
Storage Conditions
-20°C/1 year
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES2022-1.pdf
Observed Molecular Weight
140kD
Fragment
IgG
Subcellular Location
Secreted, extracellular space, extracellular matrix .
Other Product Names
COL2A1; Collagen alpha-1 (II) chain; Alpha-1 type II collagen
Gene ID (Human)
1280
Available Sizes
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