CNOT7 rabbit pAb
CCR4-NOT transcription complex subunit 7 (CNOT7) Homo sapiens The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X. [provided by RefSeq, Apr 2016],
Product Specifications
Background
UniProt
Q9UIV1
Swiss Prot
Q9UIV1
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human CNOT7. AA range:10-59
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Molecular Weight
36kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
36kD
Fragment
IgG
Subcellular Location
Nucleus. Cytoplasm, P-body . NANOS2 promotes its localization to P-body. .
Other Product Names
CNOT7; CAF1; CCR4-NOT transcription complex subunit 7; BTG1-binding factor 1; CCR4-associated factor 1; CAF-1
Gene ID (Human)
29883
Available Sizes
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