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CLK1 rabbit pAb

CDC like kinase 1 (CLK1) Homo sapiens This gene encodes a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. In the nucleus, the encoded protein phosphorylates serine/arginine-rich proteins involved in pre-mRNA processing, releasing them into the nucleoplasm. The choice of splice sites during pre-mRNA processing may be regulated by the concentration of transacting factors, including serine/arginine rich proteins. Therefore, the encoded protein may play an indirect role in governing splice site selection. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009],

Product Specifications

Background

CDC like kinase 1 (CLK1) Homo sapiens This gene encodes a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. In the nucleus, the encoded protein phosphorylates serine/arginine-rich proteins involved in pre-mRNA processing, releasing them into the nucleoplasm. The choice of splice sites during pre-mRNA processing may be regulated by the concentration of transacting factors, including serine/arginine rich proteins. Therefore, the encoded protein may play an indirect role in governing splice site selection. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]

Product Name Alternative

CLK1; CLK; Dual specificity protein kinase CLK1; CDC-like kinase 1

UniProt

P49759

Swiss Prot

P49759

Reactivity

Human; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human CLK1. AA range:101-150

Target

CLK1

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Buffer

-20°C/1 year

Molecular Weight

57kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

57kD

Fragment

IgG

Subcellular Location

Nucleus.

Other Product Names

CLK1; CLK; Dual specificity protein kinase CLK1; CDC-like kinase 1

Gene ID (Human)

1195

Available Sizes

Curated Selection

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