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Exbivirumab

Exbivirumab is a monoclonal antibody directed against highly conserved HBsAg epitopes. Exbivirumab enhances the antiviral activity of hepatitis B immunoglobulin (HBIG). Exbivirumab combined with Libivirumab decreases circulating HBsAg and hepatitis B virus (HBV) DNA levels in a chronically infected chimpanzee. Exbivirumab can be used for HBV re-infection in liver transplant[1].

Product Specifications

CAS Number

569658-80-6

UNSPSC

12352203

Target

HBV

Type

Inhibitory Antibodies

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/exbivirumab.html

Purity

97.04

Solubility

10 mM in DMSO

Smiles

[Exbivirumab]

Molecular Weight

(145.44 kDa)

References & Citations

[1]Shouval D, et al. ANTI-VIRAL EFFECTS, PHARMACOKINETICS AND SAFETY OF TWO HUMAN MONOCLONAL ANTI-HBS (LIBIVIRUMAB/EXBIVIRUMAB) VERSUS HEPATITIS B IMMUNE GLOBULIN (HBIG) IN HEPATITS B VIRUS (HBV) IN LIVER TRANSPLANT (LT) RECIPIENTS: 22[J]. Hepatology, 2006, 44: 196A. |[2]Beretta M, Mouquet H. Advances in human monoclonal antibody therapy for HBV infection. Curr Opin Virol. 2022 Apr;53:101205.

Shipping Conditions

Dry Ice

Storage Conditions

Store at -80°C for 2 years

Scientific Category

Inhibitory Antibodies

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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