CdcA3 rabbit pAb
Domain: The KEN box is required for the association with the APC/C-Cdh1 complex. function: F-box-like protein which is required for entry into mitosis. Acts by participating to E3 ligase complexes that mediate the ubiquitination and degradation of WEE1 kinase at G2/M phase. pathway: Protein modification; protein ubiquitination. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. PTM: Ubiquitinated and degraded by the APC/C-Cdh1 complex. subunit: Interacts with SKP1A. Part of a SCF (SKP1-cullin-F-box) protein ligase complex.
Product Specifications
Background
Synonyms
CDCA3; C8; GRCC8; TOME1; Cell division cycle-associated protein 3; Gene-rich cluster protein C8; Trigger of mitotic entry protein 1; TOME-1
Gene ID
83461
UniProt
Q99618
Cellular Locus
Cytoplasm, cytosol.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human CDCA3. AA range:219-268
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC, IF, ELISA
Validated Applications
WB,IHC,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Molecular Weight
28kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES1935-1.pdf
Observed Molecular Weight
28 kD
Subcellular Location
Cytoplasm, cytosol .
Other Product Names
CDCA3; C8; GRCC8; TOME1; Cell division cycle-associated protein 3; Gene-rich cluster protein C8; Trigger of mitotic entry protein 1; TOME-1
Gene ID (Human)
83461
SwissProt (Human)
Q99618
Available Sizes
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