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C6 rabbit pAb

This gene encodes a component of the complement cascade. The encoded protein is part of the membrane attack complex that can be incorporated into the cell membrane and cause cell lysis. Mutations in this gene are associated with complement component-6 deficiency. Transcript variants encoding the same protein have been described. [provided by RefSeq, Nov 2012],

Product Specifications

Background

This gene encodes a component of the complement cascade. The encoded protein is part of the membrane attack complex that can be incorporated into the cell membrane and cause cell lysis. Mutations in this gene are associated with complement component-6 deficiency. Transcript variants encoding the same protein have been described.[provided by RefSeq, Nov 2012]

Synonyms

C6; Complement component C6

Gene ID

729

UniProt

P13671

Cellular Locus

Secreted.

Host

Rabbit

Species Reactivity

Human,Rat

Reactivity

Human; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human C6. AA range:221-270

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, IHC, IF, ELISA

Validated Applications

WB,IHC,IF,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Molecular Weight

85-105kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES1810-1.pdf

Observed Molecular Weight

85 - 105 kD

Subcellular Location

Secreted.

Other Product Names

C6; Complement component C6

Gene ID (Human)

729

SwissProt (Human)

P13671

Available Sizes

Curated Selection

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