BAM32 rabbit pAb
Function: May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K. induction: Upon B-cell activation. PTM: Phosphorylated on tyrosine residues. similarity: Contains 1 PH domain. similarity: Contains 1 SH2 domain. subcellular location: Membrane-associated after cell stimulation leading to its translocation. subunit: Interacts with PtdIns (3, 4, 5)P3 and PLCG2. In vitro, interacts with PtdIns (3, 4)P2. tissue specificity: Highly expressed in placenta and lung, followed by brain, heart, kidney, liver, pancreas and skeletal muscle. Expressed by B-lymphocytes, but not T-lymphocytes or nonhematopoietic cells.
Product Specifications
Background
UniProt
Q9UN19
Swiss Prot
Q9UN19
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human DAPP1. AA range:105-154
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
32kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
32kD
Fragment
IgG
Subcellular Location
Cytoplasm . Membrane ; Peripheral membrane protein . Membrane-associated after cell stimulation leading to its translocation.
Other Product Names
Gene ID (Human)
27071
Available Sizes
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