AZI1 rabbit pAb

Caution: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. function: May play a role in spermatogenesis. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. similarity: Contains 1 IQ domain.

Product Specifications

Background

Caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data., function:May play a role in spermatogenesis., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Contains 1 IQ domain.

UniProt

Q9UPN4

Swiss Prot

Q9UPN4

Reactivity

Human; Rat; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human AZI1. AA range:311-360

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Molecular Weight

130kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

130kD

Fragment

IgG

Subcellular Location

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Cytoplasm, cytoskeleton, cilium basal body. Cytoplasmic vesicle, secretory vesicle, acrosome . Colocalized with pericentriolar material protein PCM1 at centriolar satellites. During spermiogenesis, becomes enriched with nephrocystin NPHP1 at the transition zone, a structure at the base of the ciliary axoneme important for regulating traffic into the ciliary compartment. Traffics towards and away from the centrosome/basal body and the transition zone of the ciliary axoneme in a microtubule-dependent manner. Localized at the Golgi-derived acrosome and the