Pachymic acid
Pachymic acid is a lanostrane-type triterpenoid from P. cocos. Pachymic acid inhibits Akt and ERK signaling pathways.
Product Specifications
CAS Number
[29070-92-6]
Product Name Alternative
3-O-Acetyltumulosic acid
UNSPSC
12352211
Target
Akt; ERK
Type
Natural Products
Related Pathways
MAPK/ERK Pathway; PI3K/Akt/mTOR; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Pachymic-acid.html
Purity
99.94
Solubility
DMSO : 5 mg/mL (ultrasonic) |Ethanol : 4.17 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL
Smiles
O[C@@H]([C@]1([H])[C@H](C(O)=O)CCC(C(C)C)=C)C[C@@]([C@]1(C)CC2)(C)C3=C2[C@]4(C)[C@](CC3)([H])C(C)(C)[C@@H](OC(C)=O)CC4
Molecular Formula
C33H52O5
Molecular Weight
528.76
References & Citations
[1]Chen Y, et al. Pachymic acid inhibits tumorigenesis in gallbladder carcinoma cells. Int J Clin Exp Med. 2015 Oct 15;8 (10) :17781-8.|[2]Ma J, et al. Pachymic acid induces apoptosis via activating ROS-dependent JNK and ER stress pathways in lung cancer cells. Cancer Cell Int. 2015 Aug 5;15:78.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
ERK
Available Sizes
Curated Selection
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