ARHGEF10 rabbit pAb
This gene encodes a Rho guanine nucleotide exchange factor (GEF). Rho GEFs regulate the activity of small Rho GTPases by stimulating the exchange of guanine diphosphate (GDP) for guanine triphosphate (GTP) and may play a role in neural morphogenesis. Mutations in this gene are associated with slowed nerve conduction velocity (SNCV). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015],
Product Specifications
Background
Synonyms
ARHGEF10; KIAA0294; Rho guanine nucleotide exchange factor 10
Gene ID
9639
UniProt
O15013
Cellular Locus
Centrosome,cytosol,
Host
Rabbit
Species Reactivity
Human,Monkey
Reactivity
Human; Monkey
Immunogen
The antiserum was produced against synthesized peptide derived from human ARHGEF10. AA range:339-388
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC, IF, ELISA
Validated Applications
WB,IHC,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Molecular Weight
152kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES1697-1.pdf
Observed Molecular Weight
152 kD
Subcellular Location
Centrosome, cytosol
Other Product Names
ARHGEF10; KIAA0294; Rho guanine nucleotide exchange factor 10
Gene ID (Human)
9639
SwissProt (Human)
O15013
Available Sizes
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