ARHGEF10 rabbit pAb
This gene encodes a Rho guanine nucleotide exchange factor (GEF). Rho GEFs regulate the activity of small Rho GTPases by stimulating the exchange of guanine diphosphate (GDP) for guanine triphosphate (GTP) and may play a role in neural morphogenesis. Mutations in this gene are associated with slowed nerve conduction velocity (SNCV). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015],
Product Specifications
Background
UniProt
O15013
Swiss Prot
O15013
Reactivity
Human; Monkey
Immunogen
The antiserum was produced against synthesized peptide derived from human ARHGEF10. AA range:339-388
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Molecular Weight
152kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
152kD
Fragment
IgG
Subcellular Location
Centrosome, cytosol
Other Product Names
ARHGEF10; KIAA0294; Rho guanine nucleotide exchange factor 10
Gene ID (Human)
9639
Available Sizes
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