Arginase II rabbit pAb
Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood; it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Product Name Alternative
ARG2; Arginase-2; mitochondrial; Kidney-type arginase; Non-hepatic arginase; Type II arginase
UniProt
P78540
Swiss Prot
P78540
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human ARG2. AA range:305-354
Target
Arginase II
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
38kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
38kD
Fragment
IgG
Subcellular Location
Mitochondrion .
Other Product Names
ARG2; Arginase-2; mitochondrial; Kidney-type arginase; Non-hepatic arginase; Type II arginase
Gene ID (Human)
384
Available Sizes
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