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AIFL rabbit pAb

Domain: The Rieske domain induces apoptosis. function: Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential. similarity: Belongs to the FAD-dependent oxidoreductase family. similarity: Contains 1 Rieske domain. subcellular location: Does not translocate to the nucleus upon induction of apoptosis. tissue specificity: Ubiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid gland and tongue (at protein level).

Product Specifications

Background

Domain:The Rieske domain induces apoptosis., function:Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential., similarity:Belongs to the FAD-dependent oxidoreductase family., similarity:Contains 1 Rieske domain., subcellular location:Does not translocate to the nucleus upon induction of apoptosis., tissue specificity:Ubiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid gland and tongue (at protein level) .

Synonyms

AIFM3; AIFL; Apoptosis-inducing factor 3; Apoptosis-inducing factor-like protein

Gene ID

150209

UniProt

Q96NN9

Cellular Locus

Mitochondrion. Does not translocate to the nucleus upon induction of apoptosis.

Host

Rabbit

Species Reactivity

Human,Mouse

Reactivity

Human; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human AIFM3. AA range:10-59

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, IHC, IF, ELISA

Validated Applications

WB,IHC,IF,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.

Molecular Weight

67kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES1614-1.pdf

Observed Molecular Weight

67 kD

Subcellular Location

Mitochondrion . Does not translocate to the nucleus upon induction of apoptosis.

Other Product Names

AIFM3; AIFL; Apoptosis-inducing factor 3; Apoptosis-inducing factor-like protein

Gene ID (Human)

150209

SwissProt (Human)

Q96NN9

Available Sizes

Curated Selection

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