AHA-1 rabbit pAb
Function: Cochaperone that stimulates HSP90 ATPase activity (By similarity). May affect a step in the endoplasmic reticulum to Golgi trafficking. induction: By heat shock and treatment with the HSP90 inhibitor 17-demethoxygeldanamycin (17AAG). similarity: Belongs to the AHA1 family. subcellular location: May transiently interact with the endoplasmic reticulum. subunit: Interacts with HSPCA/HSP90 and with the cytoplasmic tail of the vesicular stomatitis virus glycoprotein (VSV G). Interacts with GCH1. tissue specificity: Expressed in numerous tissues, including brain, heart, skeletal muscle and kidney and, at lower levels, liver and placenta.
Product Specifications
Background
Synonyms
AHSA1; C14orf3; HSPC322; Activator of 90 kDa heat shock protein ATPase homolog 1; AHA1; p38
Gene ID
10598
UniProt
O95433
Cellular Locus
Cytoplasm, cytosol. Endoplasmic reticulum. May transiently interact with the endoplasmic reticulum.
Host
Rabbit
Species Reactivity
Human,Rat,Mouse,
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human AHSA1. AA range:161-210
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC, IF, ELISA
Validated Applications
WB,IHC,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300; ELISA 1:5000-20000. Not yet tested in other applications.
Molecular Weight
38kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES1612-1.pdf
Observed Molecular Weight
38 kD
Subcellular Location
Cytoplasm, cytosol . Endoplasmic reticulum . May transiently interact with the endoplasmic reticulum.
Other Product Names
AHSA1; C14orf3; HSPC322; Activator of 90 kDa heat shock protein ATPase homolog 1; AHA1; p38
Gene ID (Human)
10598
SwissProt (Human)
O95433
Available Sizes
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