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AHA-1 rabbit pAb

Function: Cochaperone that stimulates HSP90 ATPase activity (By similarity). May affect a step in the endoplasmic reticulum to Golgi trafficking. induction: By heat shock and treatment with the HSP90 inhibitor 17-demethoxygeldanamycin (17AAG). similarity: Belongs to the AHA1 family. subcellular location: May transiently interact with the endoplasmic reticulum. subunit: Interacts with HSPCA/HSP90 and with the cytoplasmic tail of the vesicular stomatitis virus glycoprotein (VSV G). Interacts with GCH1. tissue specificity: Expressed in numerous tissues, including brain, heart, skeletal muscle and kidney and, at lower levels, liver and placenta.

Product Specifications

Background

Function:Cochaperone that stimulates HSP90 ATPase activity (By similarity) . May affect a step in the endoplasmic reticulum to Golgi trafficking., induction:By heat shock and treatment with the HSP90 inhibitor 17-demethoxygeldanamycin (17AAG) ., similarity:Belongs to the AHA1 family., subcellular location:May transiently interact with the endoplasmic reticulum., subunit:Interacts with HSPCA/HSP90 and with the cytoplasmic tail of the vesicular stomatitis virus glycoprotein (VSV G) . Interacts with GCH1., tissue specificity:Expressed in numerous tissues, including brain, heart, skeletal muscle and kidney and, at lower levels, liver and placenta.

UniProt

O95433

Swiss Prot

O95433

Reactivity

Human; Rat; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human AHSA1. AA range:161-210

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300; ELISA 1:5000-20000. Not yet tested in other applications.

Molecular Weight

38kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

38kD

Fragment

IgG

Subcellular Location

Cytoplasm, cytosol . Endoplasmic reticulum . May transiently interact with the endoplasmic reticulum.

Other Product Names

AHSA1; C14orf3; HSPC322; Activator of 90 kDa heat shock protein ATPase homolog 1; AHA1; p38

Gene ID (Human)

10598

Available Sizes

Curated Selection

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