Actinin-α3 rabbit pAb
This gene encodes a member of the alpha-actin binding protein gene family. The encoded protein is primarily expressed in skeletal muscle and functions as a structural component of sarcomeric Z line. This protein is involved in crosslinking actin containing thin filaments. An allelic polymorphism in this gene results in both coding and non-coding variants; the reference genome represents the coding allele. The non-functional allele of this gene is associated with elite athlete status. [provided by RefSeq, Feb 2014],
Product Specifications
Background
Synonyms
ACTN3; Alpha-actinin-3; Alpha-actinin skeletal muscle isoform 3; F-actin cross-linking protein
Gene ID
89
UniProt
Q08043
Cellular Locus
Intracellular,cytosol,actin filament,brush border,focal adhesion,Z disc,pseudopodium,extracellular exosome,
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human ACTN3. AA range:1-50
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IF, ELISA
Validated Applications
WB,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Molecular Weight
103kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES1595-1.pdf
Observed Molecular Weight
103 kD
Subcellular Location
Intracellular, cytosol, actin filament, brush border, focal adhesion, Z disc, pseudopodium, extracellular exosome
Other Product Names
ACTN3; Alpha-actinin-3; Alpha-actinin skeletal muscle isoform 3; F-actin cross-linking protein
Gene ID (Human)
89
SwissProt (Human)
Q08043
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
Cy3-Linked Monoclonal Antibody to FK506 Binding Protein 7 (FKBP7)
Cy3-Linked Monoclonal Antibody to FK506 Binding Protein 7 (FKBP7)