P120 (phospho Tyr228) rabbit pAb

Catenin delta 1 (CTNND1) Homo sapiens This gene encodes a member of the Armadillo protein family, which function in adhesion between cells and signal transduction. Multiple translation initiation codons and alternative splicing result in many different isoforms being translated. Not all of the full-length natures of the described transcript variants have been determined. Read-through transcription also exists between this gene and the neighboring upstream thioredoxin-related transmembrane protein 2 (TMX2) gene. [provided by RefSeq, Dec 2010],

Product Specifications

Background

UniProt

O60716

Swiss Prot

O60716

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human Catenin-delta1 around the phosphorylation site of Tyr228. AA range:201-250

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Molecular Weight

108kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

108kD

Fragment

IgG

Subcellular Location

Cell junction, adherens junction . Cytoplasm . Nucleus . Cell membrane . Interaction with GLIS2 promotes nuclear translocation (By similarity) . Detected at cell-cell contacts (PubMed:15240885, PubMed:17047063) . NANOS1 induces its translocation from sites of cell-cell contact to the cytoplasm (PubMed:17047063) . CDH1 enhances cell membrane localization (PubMed:15240885) . Isoforms 4A and 1AB are excluded from the nucleus (PubMed:11896187) . .; [Isoform 1A]: Nucleus .; [Isoform 2A]: Nucleus .; [Isoform 3A]: Nucleus .