Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

PKD2 (phospho Ser876) rabbit pAb

The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],

Product Specifications

Background

The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

UniProt

Q9BZL6

Swiss Prot

Q9BZL6

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human PKD2 around the phosphorylation site of Ser876. AA range:829-878

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Molecular Weight

96kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

96kD

Fragment

IgG

Subcellular Location

Cytoplasm . Cell membrane . Nucleus . Golgi apparatus, trans-Golgi network . Translocation to the cell membrane is required for kinase activation. Accumulates in the nucleus upon CK1-mediated phosphorylation after activation of G-protein-coupled receptors. Nuclear accumulation is regulated by blocking nuclear export of active PRKD2 rather than by increasing import. .

Other Product Names

PRKD2; PKD2; HSPC187; Serine/threonine-protein kinase D2; nPKC-D2

Gene ID (Human)

25865

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

NEAT1 CRISPRa sgRNA lentivector (set of three targets)(Human)
31673121 3x 1.0µg DNA

NEAT1 CRISPRa sgRNA lentivector (set of three targets)(Human)

Sign In for Pricing
View Details
Mouse UDP-glucuronosyltransferase 2A3, UGT2A3 ELISA Kit
MBS9331760-01 48 Well

Mouse UDP-glucuronosyltransferase 2A3, UGT2A3 ELISA Kit

Sign In for Pricing
View Details
Mouse UDP-glucuronosyltransferase 2A3, UGT2A3 ELISA Kit
MBS9331760-02 96 Well

Mouse UDP-glucuronosyltransferase 2A3, UGT2A3 ELISA Kit

Sign In for Pricing
View Details
Mouse UDP-glucuronosyltransferase 2A3, UGT2A3 ELISA Kit
MBS9331760-03 5x 96 Well

Mouse UDP-glucuronosyltransferase 2A3, UGT2A3 ELISA Kit

Sign In for Pricing
View Details
Mouse UDP-glucuronosyltransferase 2A3, UGT2A3 ELISA Kit
MBS9331760-04 10x 96 Well

Mouse UDP-glucuronosyltransferase 2A3, UGT2A3 ELISA Kit

Sign In for Pricing
View Details
SPT19, CT (SPATA19, SPERGEN1, Spermatogenesis-associated protein 19, mitochondrial, Spermatogenic cell-specific gene 1 protein) (MaxLight 490) discontinued
042276-ML490 100 µL

SPT19, CT (SPATA19, SPERGEN1, Spermatogenesis-associated protein 19, mitochondrial, Spermatogenic cell-specific gene 1 protein) (MaxLight 490) discontinued

Sign In for Pricing
View Details