Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

PR (phospho Ser190) rabbit pAb

This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. [provided by RefSeq, Sep 2015],

Product Specifications

Background

This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. [provided by RefSeq, Sep 2015]

Synonyms

PGR; NR3C3; Progesterone receptor; PR; Nuclear receptor subfamily 3 group C member 3

Gene ID

5241

UniProt

P06401

Cellular Locus

Nucleus. Cytoplasm. Nucleoplasmic shuttling is both hormone- and cell cycle-dependent. On hormone stimulation, retained in the cytoplasm in the G(1) and G(2)/M phases.; [Isoform A]: Nucleus. Cytoplasm. Mainly nuclear.; [Isoform 4]: Mitochondrion outer membrane.

Host

Rabbit

Species Reactivity

Human,Monkey

Reactivity

Human; Monkey

Immunogen

The antiserum was produced against synthesized peptide derived from human Progesterone Receptor around the phosphorylation site of Ser190. AA range:161-210

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, IHC, IF, ELISA

Validated Applications

WB,IHC,IF,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Molecular Weight

99kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES1397-1.pdf

Observed Molecular Weight

99 kD

Subcellular Location

Nucleus. Cytoplasm. Nucleoplasmic shuttling is both hormone- and cell cycle-dependent. On hormone stimulation, retained in the cytoplasm in the G (1) and G (2) /M phases.; [Isoform A]: Nucleus. Cytoplasm. Mainly nuclear.; [Isoform 4]: Mitochondrion outer membrane .

Other Product Names

PGR; NR3C3; Progesterone receptor; PR; Nuclear receptor subfamily 3 group C member 3

Gene ID (Human)

5241

SwissProt (Human)

P06401

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

RAD9 homolog B (RAD9B) (NM_152442) Human Tagged Lenti ORF Clone
RC208218L4 10 µg

RAD9 homolog B (RAD9B) (NM_152442) Human Tagged Lenti ORF Clone

Ask
View Details
Anti- Desmocollin 2 Antibody
GWB-18D25E 0.1 mL

Anti- Desmocollin 2 Antibody

Ask
View Details
UHRF1 AAV siRNA Pooled Vector
49152161 1.0 μg

UHRF1 AAV siRNA Pooled Vector

Ask
View Details
Recombinant Erwinia carotovora subsp. atroseptica Maltoporin (lamB)
MBS1439242-01 0.02 mg (E-Coli)

Recombinant Erwinia carotovora subsp. atroseptica Maltoporin (lamB)

Ask
View Details
Recombinant Erwinia carotovora subsp. atroseptica Maltoporin (lamB)
MBS1439242-02 0.02 mg (Yeast)

Recombinant Erwinia carotovora subsp. atroseptica Maltoporin (lamB)

Ask
View Details
Recombinant Erwinia carotovora subsp. atroseptica Maltoporin (lamB)
MBS1439242-03 0.1 mg (E-Coli)

Recombinant Erwinia carotovora subsp. atroseptica Maltoporin (lamB)

Ask
View Details