JAK1 (phospho Tyr1022) rabbit pAb
This gene encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The encoded kinase phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon-alpha/beta and interferon-gamma signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],
Product Specifications
Background
UniProt
P23458
Swiss Prot
P23458
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human JAK1 around the phosphorylation site of Tyr1022. AA range:988-1037
Clonality
Polyclonal
Source
Rabbit
Applications
IF; WB; IP; IHC; ELISA
Concentration
1 mg/ml
Dilution
IF: 1:50-200 Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
132kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
132kD
Fragment
IgG
Subcellular Location
Endomembrane system; Peripheral membrane protein. Wholly intracellular, possibly membrane associated.
Other Product Names
JAK1; JAK1A; JAK1B; Tyrosine-protein kinase JAK1; Janus kinase 1; JAK-1
Gene ID (Human)
3716
Available Sizes
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