IRS-1 (phospho Ser639) rabbit pAb
This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance. [provided by RefSeq, Nov 2009],
Product Specifications
Background
UniProt
P35568
Swiss Prot
P35568
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human IRS-1 around the phosphorylation site of Ser639. AA range:605-654
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Molecular Weight
170kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
170kD
Fragment
IgG
Subcellular Location
Nucleus, cytoplasm, cytosol, plasma membrane, insulin receptor complex, caveola, intracellular membrane-bounded organelle
Other Product Names
IRS1; Insulin receptor substrate 1; IRS-1
Gene ID (Human)
3667
Available Sizes
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