Histone H3 (phospho Ser10) rabbit pAb
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21. 3. [provided by RefSeq, Aug 2015],
Product Specifications
Background
Product Name Alternative
UniProt
P68431/Q71DI3/P84243
Swiss Prot
P68431/Q71DI3/P84243
Reactivity
Human; Mouse; Rat; Drosophila melanogaster
Immunogen
The antiserum was produced against synthesized peptide derived from human Histone H3.1 around the phosphorylation site of Ser10. AA range:1-50
Target
Histone H3
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IHC-f; Flow Cyt; ICC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. IHC: 1/100 - 1/300. ICC/IF: 1/200 - 1/1000. ELISA: 1/10000. IHC-f, Flow Cyt 1:500
Buffer
-20°C/1 year
Molecular Weight
15kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
15kD
Fragment
IgG
Subcellular Location
Nucleus. Chromosome.
Other Product Names
Gene ID (Human)
8350/8351/8352/8353/8354/8355/8356/8357/8358/8968
Available Sizes
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