Erbin (phospho Tyr1104) rabbit pAb
This gene is a member of the leucine-rich repeat and PDZ domain (LAP) family. The encoded protein contains 17 leucine-rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011],
Product Specifications
Background
UniProt
Q96RT1
Swiss Prot
Q96RT1
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized phospho-peptide around the phosphorylation site of human Erbin (phospho Tyr1104)
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
172kD
Storage Conditions
-20°C/1 year
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES1307-1.pdf
Observed Molecular Weight
172kD
Fragment
IgG
Subcellular Location
Other Product Names
ERBB2IP; ERBIN; KIAA1225; LAP2; Protein LAP2; Densin-180-like protein; Erbb2-interacting protein; Erbin
Gene ID (Human)
55914
Available Sizes
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