Bcl-2 (phospho Thr56) rabbit pAb
BCL2, apoptosis regulator (BCL2) Homo sapiens This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016],
Product Specifications
Background
BCL2, apoptosis regulator (BCL2) Homo sapiens This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
UniProt
P10415
Swiss Prot
P10415
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human BCL-2 around the phosphorylation site of Thr56. AA range:26-75
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IP; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunoprecipitation: 2-5 ug/mg lysate. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Molecular Weight
26kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
26kD
Fragment
IgG
Subcellular Location
Mitochondrion outer membrane ; Single-pass membrane protein . Nucleus membrane ; Single-pass membrane protein . Endoplasmic reticulum membrane ; Single-pass membrane protein . Cytoplasm .
Other Product Names
BCL2; Apoptosis regulator Bcl-2
Gene ID (Human)
596
Available Sizes
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