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Cleaved-MMP-23 (Y79) rabbit pAb

This gene (MMP23B) encodes a member of the matrix metalloproteinase (MMP) family, and it is part of a duplicated region of chromosome 1p36. 3. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. This gene belongs to the more telomeric copy of the duplicated region. [provided by RefSeq, Jul 2008],

Product Specifications

Background

This gene (MMP23B) encodes a member of the matrix metalloproteinase (MMP) family, and it is part of a duplicated region of chromosome 1p36.3. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. This gene belongs to the more telomeric copy of the duplicated region. [provided by RefSeq, Jul 2008]

Synonyms

MMP23A; MMP21; MMP23B; MMP21; MMP22; Matrix metalloproteinase-23; MMP-23; Femalysin; MIFR-1; Matrix metalloproteinase-21; MMP-21; Matrix metalloproteinase-22; MMP-22

Gene ID

8510

UniProt

O75900

Cellular Locus

Endoplasmic reticulum membrane ; Single-pass type II membrane protein. Membrane ; Single-pass type II membrane protein. A secreted form produced by proteolytic cleavage may also exist..

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human MMP23. AA range:60-109

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, ELISA

Validated Applications

WB,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Molecular Weight

36kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES1047-1.pdf

Observed Molecular Weight

36 kD

Subcellular Location

Endoplasmic reticulum membrane ; Single-pass type II membrane protein . Membrane ; Single-pass type II membrane protein . A secreted form produced by proteolytic cleavage may also exist. .

Other Product Names

MMP23A; MMP21; MMP23B; MMP21; MMP22; Matrix metalloproteinase-23; MMP-23; Femalysin; MIFR-1; Matrix metalloproteinase-21; MMP-21; Matrix metalloproteinase-22; MMP-22

Gene ID (Human)

8510

SwissProt (Human)

O75900

Available Sizes

Curated Selection

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