Cleaved-MMP-15 (Y132) rabbit pAb
This gene encodes a member of the peptidase M10 family and membrane-type subfamily of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Members of this subfamily contain a transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. The encoded preproprotein is proteolytically processed to generate the mature protease. This protein may play a role in cancer progression. [provided by RefSeq, Jan 2016],
Product Specifications
Background
Product Name Alternative
UniProt
P51511
Swiss Prot
P51511
Reactivity
Human; Monkey
Immunogen
The antiserum was produced against synthesized peptide derived from human MMP15. AA range:113-162
Target
MMP-15
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
61kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
61kD
Fragment
IgG
Subcellular Location
Membrane ; Single-pass type I membrane protein ; Extracellular side .
Other Product Names
Gene ID (Human)
4324
Available Sizes
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