Cleaved-MMP-10 (F99) rabbit pAb
This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down fibronectin, laminin, elastin, proteoglycan core protein, gelatins, and several types of collagen. The gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016],
Product Specifications
Background
Product Name Alternative
MMP10; STMY2; Stromelysin-2; SL-2; Matrix metalloproteinase-10; MMP-10; Transin-2
UniProt
P09238
Swiss Prot
P09238
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human MMP10. AA range:80-129
Target
MMP-10
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
43kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
43kD
Fragment
IgG
Subcellular Location
Secreted, extracellular space, extracellular matrix .
Other Product Names
MMP10; STMY2; Stromelysin-2; SL-2; Matrix metalloproteinase-10; MMP-10; Transin-2
Gene ID (Human)
4319
Available Sizes
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