Cleaved-KLK11 (I54) rabbit pAb
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in multiple transcript variants encoding distinct isoforms which are differentially expressed. [provided by RefSeq, Nov 2009],
Product Specifications
Background
Synonyms
KLK11; PRSS20; TLSP; Kallikrein-11; hK11; Hippostasin; Serine protease 20; Trypsin-like protease
Gene ID
11012
UniProt
Q9UBX7
Cellular Locus
[Isoform 1]: Secreted.; [Isoform 2]: Golgi apparatus.
Host
Rabbit
Species Reactivity
Human,Rat,Mouse,
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human Kallikrein-11. AA range:35-84
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
25kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES1039-1.pdf
Observed Molecular Weight
25 kD
Subcellular Location
[Isoform 1]: Secreted.; [Isoform 2]: Golgi apparatus.
Other Product Names
KLK11; PRSS20; TLSP; Kallikrein-11; hK11; Hippostasin; Serine protease 20; Trypsin-like protease
Gene ID (Human)
11012
SwissProt (Human)
Q9UBX7
Available Sizes
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